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The published literature describe cases in which Propranolol was used as a suicide agent. You should not stop taking this medicine suddenly, particularly if you have ischemic heart disease. Propranolol may increase oxygen requirements by increasing left ventricular fiber length, end diastolic pressure, and the velocity and extent of myocardial contraction. Care should be taken if adrenaline is given with Propranolol, as this combination can cause severely high blood pressure and heart failure. Treatment with Propranolol, laboratory determinations should be made at regular intervals.
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