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Esomeprazole reduce the production of acid in the stomach, Nexium reduces the amount of acid produced in the stomach, Nexium reduces the amount of acid produced in the stomach, Nexium reduces the amount of acid backing up into the esophagus and causing reflux symptoms. If taken on an empty stomach at least one hour before meals, swallowed whole and shouldn't be crushed or chewed. What should you watch for while taking Esomeprazole? Esomeprazole is used to treat the infection, which is responsible for the majority of gastric ulcers. Use of Esomeprazole in pregnant women has not been appraised. Nexium is a type of medicine known as an acid pump inhibitor which works by decreasing the acid produced by acid pumps. Nexium capsules should be taken at least one hour before meals and at the same time every day. There are no restrictions on food, beverages, or activities while taking Nexium, unless otherwise directed by your doctor. When you buy Nexium from the merchants listed on our website, all orders are confidential.