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Celecoxib is used to treat arthritis, acute pain, and menstrual pain and discomfort. Celecoxib is used to treat arthritis, pain, menstrual cramps, and colonic polyps. Celecoxib should only be used in pregnant women when the benefits outweigh the potential risk to the fetus. Celebrex is used to decrease growths found in the intestines of persons with a family history of this condition. Celebrex works by blocking the action of a substance in the body called cyclo-oxygenase. Celecoxib is used to decrease growths found in the intestines of persons with a family history of this condition. Celecoxib is used to decrease growths found in the intestines of persons with a family history of this condition.