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Prednisone to Prednisolone is impaired. Prednisolone is a corticosteroid used to treat various inflammatory and allergy conditions as well as other diseases. Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Prednisone is inactive in the body and, in order to be effective, first must be converted to Prednisolone by enzymes in the liver.

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