Several reports in the published literature describe cases in which Propranolol was used as a suicide agent. Propranolol from Inderal tablets is rapidly and completely absorbed from the gastrointestinal tract and undergoes extensive presystemic elimination due to its high hepatic clearance. Propranolol should be administered with caution since it may block bronchodilation produced by endogenous and exogenous catecholamine stimulation of beta-adrenergic receptors. When Propranolol is combined with another antihypertensive drug, which is a type of medicine called a beta-blocker. Propranolol is used to prevent migraine, although it is not fully understood how Propranolol works in this area. This medicine may mask the symptoms of low blood sugar such as increased heart rate, tremor and nausea. There may be increased difficulty in treating an allergic type reaction in patients on beta-blockers. Propranolol reduces the workload of the heart and so decreases its demand for oxygen.
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