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Prednisone is used in much higher doses than the levels of corticosteroids produced naturally by the body. Deltasone use is likely to change liver enzyme blood testing and interfere with testing for thyroid diseases. Prednisolone is a corticosteroid medicine. Prednisone typically does not produce immediate effects and must be used for several days before the needed effect is achieved. Your steroid medication needs may change if you have surgery or a medical emergency.

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