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Terbinafine is an allylamine medicine used to treat infections caused by fungi. Lamisil has been associated with rare cases of symptomatic hepatobiliary dysfunction including cholestatic hepatitis. Terbinafine works by stopping fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. Terbinafine inhibits a fungal enzyme, squalene epoxidase, and stops the cells making ergosterol, the main component of the cell wall. Terbinafine does not generally alter the concentration of other medications. Terbinafine tablets appear to work better than itraconazole and griseofulvin tablets. Cimetidine may decrease the breakdown of Terbinafine by the body and so may increase the blood level of Terbinafine in the blood. Terbinafine is an allylamine medicine used to treat fungal infections of the skin caused by types of fungus called dermatophytes.
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