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Valaciclovir is most effective if it is started within 48 hours of when the rash first appears. How to take the drug based on the reason it is prescribed. Anyone who has been diagnosed with genital herpes will need to discuss with your doctor. Valtrex is offered in 500 mg and 1gram tablets, the active metabolite of Valaciclovir, if appropriate. Once-daily Valtrex is also the only medication proven to reduce the amount of time for an outbreak if taken soon enough. Once-daily Valtrex is also the only medication proven to reduce the amount of time for an outbreak if taken soon enough.
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